Pancreatic Cancer Database

Annexin A1

Gene Symbol

ANXA1

Chromosome Locus

9q12-q21.2;9q12-q21.2

Alternate Names

Annexin A1; ANX1; Lipocortin I

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.5	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	4.1	Jin et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
PanIN-3	DNA microarray	Increased	2.1	Buchholz et al. 2005
Pancreatic ductal adenocarcinoma	qRT-PCR	Increased		Chen et al. 2012

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
AsPc1	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
BxPc3	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
CAPAN1	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
CAPAN2	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
CFPAC1	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
COLO357	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
Hs766T	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
MiaPaCa2	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
Panc-1	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
Su86.86	DNA microarray	Increased	5.7	Iacobuzio-Donahue et al. 2002
AsPc1	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
BxPc3	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
CAPAN1	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
CAPAN2	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
CFPAC1	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
Hs766T	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
MiaPaca2	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
Panc-1	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
Su86.86	DNA microarray	Increased	8.3	Iacobuzio-Donahue et al. 2003
AsPC-1	DNA microarray	Increased	2.9	Grutzmann et al. 2003
BxPC-3	DNA microarray	Increased	2.9	Grutzmann et al. 2003
Capan-1 Capan-2	DNA microarray	Increased	2.9	Grutzmann et al. 2003
HPAF	DNA microarray	Increased	2.9	Grutzmann et al. 2003

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	ICAT	Increased	2.3	Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Bai et al.
Acinar cell carcinoma	Immunohistochemistry	Increased		Bai et al.
Endocrine Neoplasms	Immunohistochemistry	Increased		Bai et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Bai et al.
Invasive ductal adenocarcinoma	Western blot	Increased	8.1	Crnogorac-Jurcevic et al.
Pancreatic ductal adenocarcinoma	Western blot	Increased		Chen et al. 2012
Invasive ductal adenocarcinoma	Label free quantitation, Mass spectrometry	Increased	4.4	Pan et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
BxPC-3	Western blot	Increased		Bai et al. 2004

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Label free quantitation, Mass spectrometry	Increased	2	Pan et al. 2011
Protein	Label free quantitation, Mass spectrometry	Increased	3.8	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01060	301	151690	HGNC:533

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."